# HG changeset patch # User rnateam # Date 1449768128 18000 # Node ID e0f8bc01b84b1ccdb8e7d973bf13d7f469d79813 # Parent 5f780b6d99d30389c518f6eae16d53fe450ed370 planemo upload commit 9099c0a9ff5f7f3d9407e2ec3598957e02850d88-dirty diff -r 5f780b6d99d3 -r e0f8bc01b84b mea.xml --- a/mea.xml Sat Aug 01 04:44:27 2015 -0400 +++ b/mea.xml Thu Dec 10 12:22:08 2015 -0500 @@ -1,117 +1,155 @@ - + Predict MEA structures and compare structures of RNAs + - gengetopt - mea + gengetopt + mea + - - + + + mea --version + $stdout ]]> + - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - + + - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + `_ predicts RNA maximum expected accuracy structures from RNA base pair probabilities and optionally compares them to a reference structure. In a special mode it skips the prediction and compares a +MEA predicts RNA maximum expected accuracy structures from RNA base +pair probabilities and optionally compares them to a reference +structure. In a special mode it skips the prediction and compares a given structure to the reference. For the prediction, MEA allows to penalize long base pairs, using parameters alpha, beta, gamma, and delta. For the comparison of secondary structures, several measures @@ -150,7 +188,7 @@ * TN = # true negatives -* SENS = TP/(TP+FN) 'Sensitivity'http://www.bioinf.uni-leipzig.de/Software/mea/ +* SENS = TP/(TP+FN) 'Sensitivity' * PPV = TP/(TP+FP) 'Positive Predictive Value' @@ -163,14 +201,23 @@ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ * Slide rule: tolerate shift of one base pair end by one base. This - rule directly affects the number of true positives. +rule directly affects the number of true positives. + * Conflict rule: predicted base pairs are false only if they - conflict with the reference; two base pair conflict if and only if - they share one end This rule directly affects the number of false - positives. +conflict with the reference; two base pair conflict if and only if +they share one end This rule directly affects the number of false +positives. +-------- +Download +-------- + +The command line tool MEA is free software available for download and +local installation at +.. __: http://www.bioinf.uni-leipzig.de/Software/mea/ ]]> - 10.1007/978-3-319-02624-4_1 + 10.1007/978-3-319-02624-4_1 + diff -r 5f780b6d99d3 -r e0f8bc01b84b tool_dependencies.xml --- a/tool_dependencies.xml Sat Aug 01 04:44:27 2015 -0400 +++ b/tool_dependencies.xml Thu Dec 10 12:22:08 2015 -0500 @@ -6,19 +6,22 @@ - - http://www.bioinf.uni-leipzig.de/Software/mea/mea-0.6.4.tar.gz - - - - - - - - - $INSTALL_DIR/bin - $INSTALL_DIR - + + http://www.bioinf.uni-leipzig.de/Software/mea/mea-0.6.4.tar.gz + + + + + + + + + + + + $INSTALL_DIR/bin + $INSTALL_DIR + Compiling MEA requires a C++ compiler (usually g++)