# HG changeset patch # User rnateam # Date 1381998810 14400 # Node ID 2f9d4b518b034e91dd25becc3bc34039790081ff Uploaded diff -r 000000000000 -r 2f9d4b518b03 blockbuster.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/blockbuster.xml Thu Oct 17 04:33:30 2013 -0400 @@ -0,0 +1,60 @@ + + detects blocks of overlapping reads using a gaussian-distribution approach + + blockbuster + + + blockbuster.x + -distance $distance + -minClusterHeight $minClusterHeight + -minBlockHeight $minBlockHeight + -scale $scale + -merge $merge + -tagFilter $tagFilter + -print $print + $input + + > $output + + + + + + + + + + + + + + + + + + + + +.. class:: infomark + +**What it does** + +Blockbuster_ detects blocks of overlapping reads using a gaussian-distribution approach. + + +Once short read sequences are mapped to a reference genome, one will face the problem of dividing consecutive reads into blocks to detect specific expression patterns. Due to biological variability and sequencing inaccuracies, the read arrangement does not always show exact block boundaries. The blockbuster tool automatically assigns reads to blocks and gives a unique chance to actually see the different origins where the short reads come from. + +.. _Blockbuster: http://hoffmann.bioinf.uni-leipzig.de/LIFE/blockbuster.html + + +**References** + +7. Reference + +If you use this program in your work you might want to cite: + +Langenberger D, Bermudez-Santana C, Hertel J, Hoffmann S, Khaitovitch P, Stadler PF: "Evidence for Human microRNA-Offset RNAs in Small RNA Sequencing Data", Bioinformatics (2009) vol. 25 (18) pp. 2298-301 + + + + diff -r 000000000000 -r 2f9d4b518b03 tool_dependencies.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_dependencies.xml Thu Oct 17 04:33:30 2013 -0400 @@ -0,0 +1,24 @@ + + + + + + + https://github.com/bgruening/download_store/raw/master/blockbuster/blockbuster-0.0.1.tar.gz + make + + blockbuster.x + $INSTALL_DIR/bin + + + $INSTALL_DIR/bin + + + + + Blockbuster detects blocks of overlapping reads using a gaussian-distribution approach. + GCC is needed to compilte Blockbuster. + http://hoffmann.bioinf.uni-leipzig.de/LIFE/blockbuster.html + + +