--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/muTect.xml	Wed Jul 17 12:39:36 2013 -0500
@@ -0,0 +1,107 @@
+<tool id="muTect" name="muTect" version="1.0.0">
+  <description>identify somatic point mutations</description>
+  <requirements>
+  		<requirement type="set_environment">MUTECTPATH</requirement>
+  </requirements>
+  <command interpreter="java">
+  	-Xmx2g -jar \$MUTECTPATH/muTect-1.1.1.jar
+  	--analysis_type MuTect
+  	--reference_sequence $reference
+  	#if ($cosmic.has_cosmic):
+  		--cosmic $cosmic.cosmicfile
+  	#end if
+	--dbsnp $dbsnp
+	#if str($intervals) != "" 
+  		--intervals $intervals
+  	#end if
+  	#if str($intervals) == "" and str($intervalfile) != "" 
+  		--intervals $intervalfile
+  	#end if
+	--input_file:normal $normal
+	--input_file:tumor $tumor
+	--out call_stats.txt
+	--coverage_file coverage.wig.txt	
+  </command>
+
+  <inputs>
+  	<param name="reference" type="data" format="bed, fasta" label="Select a reference genome">
+	</param>
+  	<param name="dbsnp" type="data" format="vcf" label="dbsnp.vcf file" />
+  	<param name="intervals" type="text" label="Intervals to process" help="In format 'chr1:1500-2500; chr2:2500-3500', separated by semicolons" optional="true"/>
+  	<param name="intervalfile" type="data" format="txt" label="Intervals to process (.txt file)" help="'chr1:1500-2500', one entry per line" optional="true"/>
+  	<param name="normal" type="bam" label="Normal BAM file"/>
+  	<param name="tumor" type="bam" label="Tumor BAM file"/>	
+    <conditional name="cosmic">
+		<param name="has_cosmic" type="boolean" label="Cosmic vcf file available for specimen" value="false" />
+		<when value="true">
+			<param name="cosmicfile" type="data" format="vcf" label="Cosmic vcf file"/>
+		</when>
+	</conditional>
+    	
+    	
+  </inputs>
+  
+  <outputs>
+	<data format="txt" name="callstats" label="Detailed caller output" from_work_dir="call_stats.txt"/>
+	<data format="txt" name="coverage" label="Filename for coverage output" from_work_dir="coverage.wig.txt"/>
+  	</data>
+  </outputs>
+  	
+  <help> 
+
+.. class:: infomark
+
+**License**
+
+TmuTect Revision: 44830
+GATK Revision: 2.1-202-g2fe6a31
+Copyright (c) 2012 The Broad Institute
+Please view our documentation at http://www.broadinstitute.org/gsa/wiki
+For support, please view our support site at http://getsatisfaction.com/gsa
+
+**What it does**
+
+MuTect is a method developed at the Broad Institute for the reliable 
+and accurate identification of somatic point mutations in next generation 
+sequencing data of cancer genomes.
+
+
+
+**Input**
+
+Reference Genome:
+
+	Fasta file of ref gnome
+
+Normal Sample:
+
+	bam normal sample
+
+Tumor Sample:
+
+	bam tumor sample
+
+
+Intervals:
+
+	A list of genomic intervals over which to operate.
+	
+
+
+**Output**
+
+Caller Output: 
+	
+	Detailed caller output
+
+Coverage Output:
+	
+	write out coverage in WIGGLE format to this file
+
+
+  </help>
+</tool>
+
+
+
+