Mercurial > repos > iuc > gemini
diff gemini_burden.xml @ 20:b5207530f991 draft default tip
planemo upload for repository https://github.com/galaxyproject/tools-devteam/tree/master/data_managers/data_manager_gemini_downloader commit e88029bb12e5262687267293f9d2a694eb00d3f0-dirty
| author | iuc |
|---|---|
| date | Tue, 29 Dec 2015 10:19:47 -0500 |
| parents | 27ce3de83007 |
| children |
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--- a/gemini_burden.xml Fri Oct 16 13:55:09 2015 -0400 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,82 +0,0 @@ -<tool id="gemini_@BINARY@" name="GEMINI @BINARY@" version="@VERSION@.0"> - <description>perform sample-wise gene-level burden calculations</description> - <macros> - <import>gemini_macros.xml</import> - <token name="@BINARY@">burden</token> - </macros> - <expand macro="requirements" /> - <expand macro="stdio" /> - <expand macro="version_command" /> - <command> -<![CDATA[ - gemini @BINARY@ - --cases $cases - --controls $controls - $save_tscores - $nonsynonymous - $calpha - --permutations $permutations - #if float( str($min_aaf) ) >= 0.0: - --min-aaf $min_aaf - #end if - #if float( str($max_aaf) ) >= 0.0: - --max-aaf $max_aaf - #end if - "${ infile }" - > "${ outfile }" -]]> - - </command> - <inputs> - <expand macro="infile" /> - - <param name="cases" type="text" value="" label="Space separated list of cases for association testing" help="(--cases)"/> - <param name="controls" type="text" value="" label="Space separated list of controls for association testing" help="(--controls)"/> - - <param name="save_tscores" type="boolean" truevalue="--save_tscores" falsevalue="" checked="False" - label="Save the permuted T-scores in the output file" help="(--save_tscores)"/> - - <param name="nonsynonymous" type="boolean" truevalue="--nonsynonymous" falsevalue="" checked="False" - label="Count all nonsynonymous variants as contributing burden" help="(--nonsynonymous)"/> - <param name="calpha" type="boolean" truevalue="--calpha" falsevalue="" checked="False" - label="Run the C-alpha association test" help="(--calpha)"/> - <param name="min_aaf" type="float" value="-1" label="The min. alt. allele frequency for a variant to be included" - help="(--min-aaf)"> - <!--validator type="in_range" min="0.0"/--> - </param> - <param name="max_aaf" type="float" value="-1" label="The max. alt. allele frequency for a variant to be included" - help="(--max-aaf)"> - <!--validator type="in_range" min="0.0"/--> - </param> - - <param name="permutations" type="integer" value="1000" label="Number of permutations to run for the C-alpha test" - help="(--permutations)"> - <validator type="in_range" min="0"/> - </param> - - </inputs> - <outputs> - <data name="outfile" format="tabular" /> - </outputs> - <tests> - <test> - </test> - </tests> - <help> -**What it does** - -The burden tool provides a set of utilities to perform burden summaries on a per-gene, per sample basis. -By default, it outputs a table of gene-wise counts of all high impact variants in coding regions for each sample. - -$ gemini burden test.burden.db -gene M10475 M10478 M10500 M128215 -WDR37 2 2 2 2 -CTBP2 0 0 0 1 -DHODH 1 0 0 0 - -@CITATION@ - </help> - <expand macro="citations"> - <citation type="doi">10.1371/journal.pgen.1001322</citation><!-- c-alpha citation --> - </expand> -</tool>
