Mercurial > repos > iuc > gemini
diff gemini_lof_sieve.xml @ 17:65f742e605ec draft
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/gemini commit 344140b8df53b8b7024618bb04594607a045c03a
| author | iuc |
|---|---|
| date | Mon, 04 May 2015 22:46:38 -0400 |
| parents | 53a5647e5271 |
| children |
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--- a/gemini_lof_sieve.xml Tue Apr 28 22:55:56 2015 -0400 +++ b/gemini_lof_sieve.xml Mon May 04 22:46:38 2015 -0400 @@ -1,11 +1,12 @@ <tool id="gemini_@BINARY@" name="GEMINI @BINARY@" version="@VERSION@.0"> <description>Filter LoF variants by transcript position and type</description> - <expand macro="requirements" /> - <expand macro="version_command" /> <macros> <import>gemini_macros.xml</import> <token name="@BINARY@">lof_sieve</token> </macros> + <expand macro="requirements" /> + <expand macro="stdio" /> + <expand macro="version_command" /> <command> <![CDATA[ gemini @BINARY@ @@ -13,7 +14,6 @@ > "${ outfile }" ]]> </command> - <expand macro="stdio" /> <inputs> <expand macro="infile" /> </inputs> @@ -27,10 +27,10 @@ <help> **What it does** -Not all candidate LoF variants are created equal. For e.g, a nonsense (stop gain) variant impacting the first 5% of a polypeptide is far -more likely to be deleterious than one affecting the last 5%. Assuming you’ve annotated your VCF with snpEff v3.0+, the lof_sieve tool -reports the fractional position (e.g. 0.05 for the first 5%) of the mutation in the amino acid sequence. -In addition, it also reports the predicted function of the transcript so that one can segregate candidate +Not all candidate LoF variants are created equal. For e.g, a nonsense (stop gain) variant impacting the first 5% of a polypeptide is far +more likely to be deleterious than one affecting the last 5%. Assuming you’ve annotated your VCF with snpEff v3.0+, the lof_sieve tool +reports the fractional position (e.g. 0.05 for the first 5%) of the mutation in the amino acid sequence. +In addition, it also reports the predicted function of the transcript so that one can segregate candidate LoF variants that affect protein_coding transcripts from processed RNA, etc. @CITATION@
