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planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools commit 73ebd55430874a3c1483b6dd6cce0482175482f9
author iuc
date Fri, 21 Feb 2025 21:38:34 +0000
parents 539958feb49c
children
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1d0a0d6a78b1 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools commit 1e25e8d0bd1ebeb2b94c4bbdff222e56defc1fc2"
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1 <tool id="bedtools_reldistbed" name="bedtools ReldistBed" version="@TOOL_VERSION@" profile="@PROFILE@">
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2 <description>calculate the distribution of relative distances</description>
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3 <macros>
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4 <import>macros.xml</import>
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5 </macros>
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6 <expand macro="bio_tools" />
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7 <expand macro="requirements" />
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8 <expand macro="stdio" />
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df28283b3778 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools commit b68002321ade5e160c556517a98ffb70f068be95
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9 <command><![CDATA[
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10 bedtools reldist
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11 -a '$inputA'
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12 -b '$inputB'
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13 $detail
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14 > '$output'
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15 ]]></command>
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16 <inputs>
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17 <param name="inputA" argument="-a" type="data" format="bam,@STD_BEDTOOLS_INPUTS@" label="@STD_BEDTOOLS_INPUT_LABEL@/BAM file"/>
df28283b3778 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools commit b68002321ade5e160c556517a98ffb70f068be95
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18 <param name="inputB" argument="-b" type="data" format="@STD_BEDTOOLS_INPUTS@" label="@STD_BEDTOOLS_INPUT_LABEL@ file"/>
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19 <param argument="-detail" type="boolean" truevalue="-detail" falsevalue="" checked="false"
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20 label="Instead of a summary, report the relative distance for each interval in A" />
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21 </inputs>
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22 <outputs>
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23 <data name="output" format_source="inputA" metadata_source="inputA" label="Relalative distance of ${inputA.name} and ${inputB.name}"/>
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24 </outputs>
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25 <tests>
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26 <test>
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27 <param name="inputA" value="a.bed" ftype="bed" />
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28 <param name="inputB" value="a.bed" ftype="bed" />
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29 <output name="output" file="reldistBed_result1.bed" ftype="bed" />
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30 </test>
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31 </tests>
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32 <help><![CDATA[
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33 **What it does**
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35 Traditional approaches to summarizing the similarity between two sets of genomic intervals are based upon the number or proportion of intersecting intervals. However, such measures are largely blind to spatial correlations between the two sets where, dpesite consistent spacing or proximity, intersections are rare (for example, enhancers and transcription start sites rarely overlap, yet they are much closer to one another than two sets of random intervals). Favorov et al proposed a relative distance metric that describes distribution of relative distances between each interval in one set nd the two closest intervals in another set (see figure above). If there is no spatial correlation between the two sets, one would expect the relative distances to be uniformaly distributed among the relative distances ranging from 0 to 0.5. If, however, the intervals tend to be much closer than expected by chance, the distribution of observed relative distances would be shifted towards low relative distance values (e.g., the figure below).
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37 .. image:: $PATH_TO_IMAGES/reldist-glyph.png
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39 .. class:: infomark
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41 @REFERENCES@
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42 ]]></help>
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43 <expand macro="citations">
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44 <citation type="doi">10.1371/journal.pcbi.1002529</citation>
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45 </expand>
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46 </tool>