LOCUS       STANORAX                1601 bp    DNA     linear   BCT 27-MAY-1993
DEFINITION  Staphylococcus aureus fluoroquinolone resistance protein (norA)
            gene, complete cds.
ACCESSION   M97169
VERSION     M97169.1
KEYWORDS    fluoroquinolone resistance protein; norA gene.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 1601)
  AUTHORS   Kaatz,G.W., Seo,S.M. and Ruble,C.A.
  TITLE     Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus
  JOURNAL   Antimicrob. Agents Chemother. 37 (5), 1086-1094 (1993)
   PUBMED   8517696
FEATURES             Location/Qualifiers
     source          1..1601
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:1280"
     gene            117..1412
                     /gene="norA"
     regulatory      117..122
                     /regulatory_class="minus_35_signal"
                     /gene="norA"
                     /note="putative"
     regulatory      141..146
                     /regulatory_class="minus_10_signal"
                     /gene="norA"
     CDS             246..1412
                     /gene="norA"
                     /function="fluoroquinolone efflux"
                     /standard_name="NORA1199 wild-type gene"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAA26658.1"
                     /translation="MNKQILVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLV
                     AAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAIGQNFLILMLSRVIGG
                     MSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFY
                     FAGALGILAFIMSIVLIHDPKKVSTNGFQKLEPQLLTKINWKVFITPVILTLVLSFGL
                     SAFETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSL
                     IYSVIVLVLLVIADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAGDRQGFAGGLNST
                     FTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKQQDL"
ORIGIN
        1 ctagtagtat agtatgatta cttttttgca atttcatatg atcaatcccc tttattttaa
       61 tatgtcatta attatacaat taaatggaaa atagtgataa ttacaaagaa aaaatattgt
      121 caaatgtagc aatattgtaa tacaatatag aaacttttta cgaatattta gcatgaattg
      181 caatctgtcg tggaaaagaa aaataacagc ttgaagagtg acaagtagaa aaaagaggtg
      241 agcaaatgaa taaacagatt ttggtattat attttaatat tttcttaatt tttttaggta
      301 tcggtctagt gataccagtc ttacctgttt atttaaaaga tttggggtta actggtagtg
      361 atttaggatt attagttgct gctttcgcct tatctcaaat gattatatcg ccattcggtg
      421 gtacgttagc tgataaatta ggaaagaaat taattatatg tataggatta attttgtttt
      481 cagtgtcaga atttatgttt gctatcggtc agaatttttt aattttgatg ttatcaaggg
      541 ttatcggtgg tatgagtgct ggtatggtta tgcctggggt gacaggttta atagctgata
      601 tttcaccaag ccatcaaaaa gcaaaaaact ttggctacat gtcagcgatt atcaattcag
      661 gattcatttt aggaccaggg attggtggat ttatggcaga agtttcacat cgtatgccat
      721 tttattttgc aggtgcatta ggtattctag catttataat gtcaattgta ttgattcacg
      781 accctaaaaa agtttcgaca aatggattcc aaaagttgga gccacaattg ctaacgaaaa
      841 ttaactggaa agtgtttatt acaccagtta ttctaacact tgtattatcg tttggtttat
      901 ctgcatttga aacattgtat tcactataca cagctgacaa ggtaaattat tcacctaaag
      961 atatttcgat tgcaattaca ggtggcggta tctttggtgc acttttccaa atttatttct
     1021 ttgataaatt tatgaaatac ttctctgagt taacatttat tgcatggtca ttaatatatt
     1081 cagttattgt attagtgcta ttagttattg ccgatggtta ctggacaatt atggtaataa
     1141 gctttgttgt ctttatcggg ttcgatatga taagacctgc tattacaaat tatttttcaa
     1201 atattgctgg tgatagacag ggatttgcag gtgggttaaa ctcaacattc actagcatgg
     1261 ggaattttat aggtccttta atcgcaggtg cgttatttga tgtgcacatt gaagccccaa
     1321 tttatatggc tataggtgtg tcattagctg gtgttgtcat tgttttaatt gaaaagcaac
     1381 atagagctaa gttaaaacaa caagatttgt aatatcgcac atggttgtca ttcgattaat
     1441 gtttttcgac aactaaagca tttcaaaata agcatcgatt ttcttacaat tatagtgaag
     1501 aaaagtcgat gctttaaatt tataaagatt aaaaactttt aaatgtttta gtctttatat
     1561 ttaaatgtta tatgtaacaa aaaatgattt tgagtaataa a
//
