LOCUS       CP021680               23332 bp    DNA     circular BCT 08-JUN-2017
DEFINITION  Escherichia coli strain AR_0162 plasmid tig00002623, complete
            sequence.
ACCESSION   CP021680
VERSION     CP021680.1
DBLINK      BioProject: PRJNA292902
            BioSample: SAMN04015003
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23332)
  AUTHORS   Conlan,S., Thomas,P.J., Mullikin,J., Frank,K.M. and Segre,J.A.
  TITLE     Whole genome sequencing of Escherichia coli AR_0162
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23332)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2017) NIH Intramural Sequencing Center, 5625
            Fishers Lane, Rockville, MD 20852, USA
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method       :: canu v. 1.3
            Genome Coverage       :: 154x
            Sequencing Technology :: PacBio RSII
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 03/28/2017 16:33:15
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS+
            Annotation Software revision      :: 4.1
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 5,230
            CDS (total)                       :: 5,110
            Genes (coding)                    :: 4,838
            CDS (coding)                      :: 4,838
            Genes (RNA)                       :: 120
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 272
            Pseudo Genes (ambiguous residues) :: 0 of 272
            Pseudo Genes (frameshifted)       :: 124 of 272
            Pseudo Genes (incomplete)         :: 118 of 272
            Pseudo Genes (internal stop)      :: 87 of 272
            Pseudo Genes (multiple problems)  :: 52 of 272
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23332
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="AR_0162"
                     /db_xref="taxon:562"
                     /plasmid="tig00002623"
     gene            join(23242..23332,1..1913)
                     /locus_tag="AM408_00005"
     CDS             join(23242..23332,1..1913)
                     /locus_tag="AM408_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002415432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter"
                     /protein_id="ARX12228.1"
                     /translation="MIMSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVAD
                     KNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFA
                     MLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAI
                     VALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGV
                     LQVNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLL
                     ALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLS
                     WSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATDLAN
                     TVQQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTP
                     VWQRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLT
                     KRESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNK
                     QGTISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRY
                     YRAEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            1858..2016
                     /locus_tag="AM408_00010"
     CDS             1858..2016
                     /locus_tag="AM408_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001437314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter"
                     /protein_id="ARX12229.1"
                     /translation="MTYWTSTKNTCTSCTWFVNSNMPSWGRQLLSRPQYEGMQNDFTL
                     EMDAEADN"
     gene            1976..3253
                     /locus_tag="AM408_00015"
     CDS             1976..3253
                     /locus_tag="AM408_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ARX12230.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSINTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPEIFAEAAHTLAFETL
                     EHATRADHIDSDRYLIKSTYYNLFSGEYSNKKT"
     gene            complement(3533..4695)
                     /locus_tag="AM408_00020"
                     /pseudo
     CDS             complement(3533..4695)
                     /locus_tag="AM408_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(4846..5543)
                     /locus_tag="AM408_00025"
                     /pseudo
     CDS             complement(4846..5543)
                     /locus_tag="AM408_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            5733..5810
                     /locus_tag="AM408_00030"
                     /pseudo
     CDS             5733..5810
                     /locus_tag="AM408_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005016182.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
     gene            5835..6356
                     /locus_tag="AM408_00035"
     CDS             5835..6356
                     /locus_tag="AM408_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Member of the extracytoplasmic function sigma
                     factors which are active under specific conditions; binds
                     with the catalytic core of RNA polymerase to produce the
                     holoenzyme and directs bacterial core RNA polymerase to
                     specific promoter elements to initiate transcription; this
                     sigma factor regulates the genes for iron dicitrate
                     transport; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="ARX12231.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            6353..7306
                     /locus_tag="AM408_00040"
     CDS             6353..7306
                     /locus_tag="AM408_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="with FecA forms the FecAR signal transduction
                     system; ferric citrate binds FecA and transmits a signal
                     across the outer membrane to FecR. FecR transmits a signal
                     across the cytoplasmic membrane and activates the sigma 70
                     protein FecI that directs the RNA polymerase to express
                     the fecABCDE operon; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron dicitrate transport regulator FecR"
                     /protein_id="ARX12232.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TSEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            7393..9717
                     /locus_tag="AM408_00045"
     CDS             7393..9717
                     /locus_tag="AM408_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="ARX12233.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPIS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDHFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHKEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            9762..10664
                     /gene="fecB"
                     /locus_tag="AM408_00050"
     CDS             9762..10664
                     /gene="fecB"
                     /locus_tag="AM408_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="part of the ABC transporter involved in the uptake
                     of citrate-dependent Fe(3+); Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate transporter substrate-binding
                     subunit"
                     /protein_id="ARX12234.1"
                     /translation="MLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            10661..11659
                     /gene="fecC"
                     /locus_tag="AM408_00055"
     CDS             10661..11659
                     /gene="fecC"
                     /locus_tag="AM408_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="part of the FecBCDE citrate-dependent iron (III)
                     transport system; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate transporter permease subunit"
                     /protein_id="ARX12235.1"
                     /translation="MTAIKHPMLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            11656..12612
                     /gene="fecD"
                     /locus_tag="AM408_00060"
     CDS             11656..12612
                     /gene="fecD"
                     /locus_tag="AM408_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Ferric citrate binds FecA and is transported across
                     the outer membrane while transmits a signal across the
                     cytoplasmic membrane protein FecR. FecR transmits a signal
                     across the membrane and activates the cytoplasmic FecI
                     that directs the RNA polymerase to express the fecABCDE
                     operon (which encodes the ferric citrate outer membrane
                     receptor and the ferric citrate ABC transporter), as well
                     as fecIR. FecD is one of two (along with FecC) integral
                     membrane protein components of the iron dicitrate ABC
                     transporter; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate transporter subunit FecD"
                     /protein_id="ARX12236.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            12613..13380
                     /locus_tag="AM408_00065"
     CDS             12613..13380
                     /locus_tag="AM408_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport ATP-binding protein
                     FecE"
                     /protein_id="ARX12237.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(13937..14350)
                     /locus_tag="AM408_00070"
     CDS             complement(13937..14350)
                     /locus_tag="AM408_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002415437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ARX12238.1"
                     /translation="MVGYHQTNQKTDTGKTLTRRPVLVDHNRLPEGSRGRLAVAVAGD
                     HPAAVQVTMTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFPLAKKGE
                     GRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
     gene            complement(14277..14763)
                     /locus_tag="AM408_00075"
                     /pseudo
     CDS             complement(14277..14763)
                     /locus_tag="AM408_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="frameshifted; internal stop; incomplete; partial on
                     complete genome; missing start; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(14844..15700)
                     /locus_tag="AM408_00080"
                     /pseudo
     CDS             complement(14844..15700)
                     /locus_tag="AM408_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001436454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            16653..17092
                     /locus_tag="AM408_00085"
                     /pseudo
     CDS             16653..17092
                     /locus_tag="AM408_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640681.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17019..17733)
                     /locus_tag="AM408_00090"
                     /pseudo
     CDS             complement(17019..17733)
                     /locus_tag="AM408_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            17937..18752
                     /locus_tag="AM408_00095"
                     /pseudo
     CDS             17937..18752
                     /locus_tag="AM408_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242429.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate transporter"
     gene            19328..19854
                     /locus_tag="AM408_00100"
                     /pseudo
     CDS             19328..19854
                     /locus_tag="AM408_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945844.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 1"
     gene            19936..20765
                     /locus_tag="AM408_00105"
                     /pseudo
     CDS             19936..20765
                     /locus_tag="AM408_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001411476.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirG localization protein VirK"
     gene            20830..21774
                     /locus_tag="AM408_00110"
     CDS             20830..21774
                     /locus_tag="AM408_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="ARX12239.1"
                     /translation="MKKYKSEFIPEFKKNYLSPVYWSTWFLLGMIAGISMFPPSFRDP
                     VLAKIGRWAGRLSKKARRRATINLSLCFPEKSDTEREIIVDKMFITALQSIVMMAELA
                     IRGPEKFQKRVFWKGLEILEEIRHNNRNVIFLVPHGWSVDIPAMLLAAQGKKMAAMFH
                     QQRNPVIDYVWNSVRRKFGGRLHAREDGIKPFIQSVRQGYWGYYLPDQDHGPEYSEFA
                     DFFATYKATLPIIGRLMNISQAMIIPLFPVYDEKKHLLTIEIRPPMDACIASADNKTI
                     ARQMNKTVEILVGPHPEQYVWVLKLLKTRKSNEADPYP"
     gene            21955..23094
                     /locus_tag="AM408_00115"
     CDS             21955..23094
                     /locus_tag="AM408_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="ARX12240.1"
                     /translation="MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQW
                     VTAARKGLGTPGSRTVAELESEILQLRKALNEARLERDILNCTGVAEKYALIEQWRQQ
                     FPIEAMCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETYGTRRLQTE
                     LAENGIIVGRDRLARLRKELRLRCKQKRKFRATTNSNHNLPVAPNLLNQTFAPTAPNQ
                     VWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMALRSQRPPA
                     GLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYR
                     FNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
ORIGIN      
        1 ttcttgtcgc ctttgccgcc gtattcccgg atgtcgccga caaaaatttt aaactacttc
       61 agcaacaaat cttcacgaat gccagctggt tctacatcct tgctgtggcc ctgattttac
      121 tgagtgtcac gttccttgga ctctcacgct acggtgatat caagctgggc ccggaccatg
      181 cgcagcctga tttcagctac cactcctggt ttgcgatgct tttttcggca gggatgggga
      241 tcggcctgat gttctttggc gttgccgaac ctgtaatgca ttatctttcg ccacccgttg
      301 gcactccaga aaccgttgcg gcagctaagg aagcaatgcg tctgaccttt ttccactggg
      361 gactgcacgc atgggcaatt tatgccattg tggcgctgat tctggcgttc ttcagttacc
      421 gtcacggtct gcctttaact ctgcgctccg cactctatcc cattattggc gatcgcatat
      481 acggacctgt aggacatgcg gttgatattt tcgctgttat aggcacggtc tttggcgttg
      541 cgacatcact gggttacggt gttttgcagg tgaatgccgg tttgaaccat cttttcgggg
      601 tgcccatcaa tgaaacggtg caggtaattc tgatcgtggt catcacgggg ttagcgacga
      661 tttcagtggt gtccggtctg gataagggaa tacgtatcct gtctgaactc aatctgggtc
      721 tggctttgtt gctcctggcg ctggtcctgt gtctgggacc aaccgtgctt ctgctgaagt
      781 catttgtgga aaatacgggc ggttatcttt cggaactggt gagtaaaacg ttcaaccttt
      841 acgcgtatga gcccaagtcg agcaactggc tggggggctg gacattactg tactggggat
      901 ggtggctttc atggtcgccg tttgtgggga tgttcatcgc acgggtctcc cgcgggcgaa
      961 ccattcgcga gtttgtcacc ggcgtgctgt ttgttcccgc gggttttacg ctaatgtgga
     1021 tgacggtgtt tggtaacagc gcgatctatc tcattatgaa ccagggggcc acagacctcg
     1081 ccaatactgt tcagcaggat gtggcgctgg ccctgtttaa tttcctggag catttcccgt
     1141 tctcttctgt gctgtcattc attgcaatgg cgatggtcat cgtcttcttt gtaacgtctg
     1201 ctgattcggg ggcaatggtt gtggatactc tggcatcagg tggagtggca aacacacccg
     1261 tctggcagcg aatattctgg gcctcgctca tgggcattgt tgcaattgcg cttctccttg
     1321 ccggagggct aagtgcgctg caaacggtga caatagcgag tgcattgccc ttctcagtga
     1381 tcttactaat atctatatac ggacttttaa aagctttgcg ccgggatttg accaagcgtg
     1441 aaagcctgag catggcgaca attgctccta cggctgcacg taacccaatt ccttggcaga
     1501 gaaggttacg caatatcgcg tatctgccga agcgatctct tgtgaaacgt tttatggacg
     1561 acgttatcca gcctgccatg acgctggttc aggaggaact gaacaagcag gggacgataa
     1621 gccacattag tgatgcagtc gacgatcgta ttcgtcttga agtcgatttg ggcaacgagc
     1681 tgaattttat atatgaagtg aggcttcgcg ggtatatctc accgaccttc gcgctcgccg
     1741 caatggataa tgatgagcag cagactgaac aacatcgata ttatcgcgct gaggtttatc
     1801 tcaaagaagg cggtcaaaat tatgatgtga tgggctggaa ccaggaacag ctgattaatg
     1861 acatactgga ccagtacgaa aaacacctgc acttcctgca cctggttcgt taatagcaac
     1921 atgccgtcct gggggcggca attattatcc cggccgcaat atgagggaat gcagaatgat
     1981 ttcacgctgg aaatggatgc tgaagcagac aattaaaaaa ctatggttca gggcaacgtt
     2041 attcgcaatt gtcgcgataa taacggccct tttatcaatt ctttttaaat caatgatacc
     2101 tgagtcggtt tccgtgaagg ttggtgcgga agcagtcgat aacattctga acatactggc
     2161 atcgagtatg ctggcagtga ccacattttc gctgagtatc atggtcacag cctacggttc
     2221 agccactact aatgtgactc ccagagctac gcgtttagtt gttgaagacg tcaccacaca
     2281 aaatgtactg gccaccttca tcggttcttt tctcttcagt ctggtaggga ttattgccct
     2341 caatatggga gcttatggag aaagggggag agtcatttta ttcattgtca cactggttgt
     2401 cattgcctta atcctcatca cattgcttcg ctggatacag catttgacct ctctggggag
     2461 ggttggtgag acaacggcac aagtagaaca ggcggccatc gaaacattta ttgcgagagc
     2521 aagaaatccc tgtctcggtg gatatccatg gcttgagaac aatgaacagc cgaaaggaac
     2581 ggttgcagtt tatccgaaga agattggcta tgttgaatat attgatatgg tgaaacttag
     2641 caagctgctg accaatgatc cccgtcatgt atacctcgtg gcgcagccag gcagtttcat
     2701 acatccgtcc atgccagttt tgtacctgag tcagggccag gagtcgtcaa tcaacaccga
     2761 tttacttgag acgattattg tctcggatgc acgttcattt gctcaggatc ctcgattttg
     2821 tcttagcgtc atggccgaaa tagcctgccg ggccctttcc cctgcagtga acgatcctgg
     2881 aaccgccatt gatgtcattg gcagaggtgt tcgtatactt tccacttacg cgcagaataa
     2941 atctgatgaa atagaagtga aatatccttc agtacatgtt gcaccacttc agaataacga
     3001 tctactggaa gactttttct cacctgtcgc gcgcgatggt gccagtatga gggagattca
     3061 gataagagtc cttaaaggac tgtcgatgct gagtaaaggt tggcctgaga tatttgctga
     3121 agccgcacat accctggcat ttgaaacatt agagcatgca actcgtgctg accatataga
     3181 ttctgataga tatctaataa aatcaactta ttataattta tttagtggcg aatattctaa
     3241 taaaaaaaca tagctgcaga gcaagcaatt cggttgttgg caagtcaagg gcaaagcatt
     3301 cgcgtgagaa tgggcgtatg ctttgtgcca aaagcaaacg ttgctaattc tgcactgttc
     3361 agcgatggcg cagtagagac aggcactgcc actgtccagt cggcaaaagc gaacactttg
     3421 ccactgcggg gataaactga ttgaagctct cgcgcaaaat cacttattct tttgcgttaa
     3481 taaaatgtag gagatgggtc attgatccta cccacgtaat atggacacag gcctaagcga
     3541 ggttcttgtt ttcaaattgt tccggactga ggccgccaca ccaactgtgc cgccgccacc
     3601 gattgtaatc acattcgata taattaaaca ccgttgcccg cattatttcc cggctgataa
     3661 agtgttctcc atggatacat tccactttca gcgaatgaaa gaagctttcc acgcaggcat
     3721 tatcgtagca gcaacctttt gcgctcatac ttccacgcag attatgccgc ttcagttgcg
     3781 cctgataatc tgctgaacag tactggcctc cacggtccgt gtgaacgata acgttccggg
     3841 gcctcgtacg ccgccatagc gccatctgca gggcatcgca ggccagttgc gccgtcatgc
     3901 gtggcgacat tgaccagcca ataacggcac gtgaccacag gtcaatgacc actgccagat
     3961 acagccagcc ttcatctgta cgtaagtacg tgatgtctcc tgcccacttc tggttcgggc
     4021 cactggtgta aaaatcctgc tccaacagat tttctgatac aggcaggccg tgtgcgcggt
     4081 agctgaccgg gctgaacttc cgggaggcct ttgccctcag tccctgacgg cgcaggcttg
     4141 ccgccacggt ttttacgtta aaggggtaac cctgagcacg cagttcatcc gtcaggcgtg
     4201 gggcaccgta acgctgtttt gaccgggtaa aagccgcgag gacaacgctg tcgcagtgtt
     4261 ggcggaactg ctgacgcgtg cttatccttg tccgccgctg acaccacgta taccagccgc
     4321 tgcgggccac ccggagcacg cggcacattg ctttgatgct gaactcagcc tgatgttttt
     4381 caataaagac atacttcatt tcaggcgctt cgcgaagtat gtcgcggcct tttggaggat
     4441 agccagctct tcatcccgtt ctgccagctg gcgtttgaga cgtgcaatct cggtagacat
     4501 ctccagttca cgttcagaag acgtctgctg attttgctgt ttactgcgcc agttgtagag
     4561 ctgtgattca tacaggctga gttcacgggc tgcggcagta acaccgatgc gttcagcaag
     4621 cttcagggct tcactgcgaa attcaggcga atgctgttta cggggttttt tactggttga
     4681 tactgttttt gtcatgtgag tcacctctga ctgagagttt actcacttag ccgcgtgtcc
     4741 actattgctg ggtaagatca caacacttta aaatgcccta tatagggtta accagtaatt
     4801 atctgtatga tagctttgag ttcgggagga ggtaatgact ccaacttact gatagtgttt
     4861 tatgttcaga taatgcccga tgaccttgtc atgcagctcc accgattttg agaacgacag
     4921 tgacttccgt cccagccttg ccagatgttg tctcagattc agattatgtc gctcaatgcg
     4981 ctgagtgtaa cgcttgctga taacgtgcag ctttcccttc aggcgtgatt catacagcgg
     5041 ccagccatcc gtcatctata ccacgacctc aaaggccgac agcaggctca gaagacgctc
     5101 cagtgtggcc agagtgcgtt caccgaagac gtgcgccaca accgtcctcc gtatcctgtc
     5161 atacgcgtaa aacagccagc gctgacgtga tttagcaccg acgtagcccc actgttcgtc
     5221 catttcagcg cagacaatca catcactgcc cggttgtatg cgcgaggtta ccgactgcga
     5281 cctgagtttt ttaagtgacg taaaaccgtg ttgaggccaa cgcccataat gcgtgcactg
     5341 gcgcgacatc cgacgccatt catggccata tcaatgattt tctggtgcgt accgggctga
     5401 gaggcggtgt aagtgaactg tagttgccat gttttacggc aatgagagca gagatagcgc
     5461 tgatgtccgg cagtgctttt gccgttacgc accacgcctt cagtagcgga gcaggaagga
     5521 catctgatgg aaatggaagc cacgcaagca ccttaaaatc accatcatac actaaatcag
     5581 taagttggca gcattaccga aatccccatc ctttagggca gtgaggatgt caataatagc
     5641 agaccacatc atgagtcatt ctgaccgaca catgccagaa gcagaggctc catcccattt
     5701 tatacctacc ttataacact tagaaaaaca acatgttaaa aatgtctatt ggaaacaatt
     5761 ttatttccaa ttgtaatgat aaccattctc atattaatat gactacgtga taattaactt
     5821 ttgatgcact ccgcatgtct gaccgcgcca ctaccacagc ttccttaacg ttcgagtcgc
     5881 tttatggcac acatcacggc tggttgaaaa gctggctgac gcgcaaactc cagtctgctt
     5941 ttgatgcaga tgacattgcc caggacactt ttttgcgggt aatggtcagc gaaacgctct
     6001 cgacgatccg cgatcctcgc tccttcctct gcactatcgc caaacgcgtg atggtggacc
     6061 tgtttcgccg aaacgcgctg gaaaaagcgt atctggagat gctggcgctt atgccggagg
     6121 ggggagcgcc ttcacctgag gaacgcgaaa gccaactcga gaccctacaa ctcctcgaca
     6181 gcatgctgga cgggctaaac ggcaaaacac gtgaagcgtt tctgctttcg caactggatg
     6241 gtctgacata cagcgagatt gcgcacaaac tcggtgtttc catcagctcc gtgaaaaaat
     6301 acgtggcgaa agccgtcgag cactgcctgc tgttccgtct ggagtatggg ttatgaatcc
     6361 tttgttaacc gattcccgcc gtcaggcgct gcgttcagct tcccactggt atgccgtgct
     6421 aagcggcgag cgcgtcagcc cacaacagga agcgcgctgg caacagtggt atgaacagga
     6481 tcaggataac cagtgggcct ggcagcaggt tgaaaacctg cgcaaccagc ttggcggtgt
     6541 gcctggcgac gttgccagcc gggcgttgca cgatacccgc ctcacccgcc gtcacgtgat
     6601 gaaaggatta ctgctgttgc tcggcgctgg cggaggctgg cagctctggc agtcggaaac
     6661 cagcgaaggt ctgcgggcag attaccgcac cgccaaaggc acagtcagcc gccagcaact
     6721 ggaagatggc tccctgctca cgctgaatac ccaaagcgcg gcggatgtgc gttttgatgc
     6781 gcatcagcgc accgtccggc tctggtacgg tgaaatcgcc attactaccg cgaaagatgc
     6841 cctgcaacgc cccttccgtg tcctgacccg tcagggccag ctcactgctt tagggacaga
     6901 atttaccgtc cgccagcagg ataatttcac gcagcttgac gtgcagcagc acgctgtgga
     6961 agtgcttctc gccagtgccc ccgcgcaaaa acgcatcgtg aacgctggtg aaagcctgca
     7021 gttcagcgcc tctgagtttg gcgcagtgaa accgctggat gacgagagta caagctggac
     7081 gaaggacatc ctgagcttca gcgataaacc gctgggtgag gtgatagcca cgctaacccg
     7141 ttaccgcaac ggagtgctgc gctgcgatcc cgccgttgcc gggctgcgcc tgagcgggac
     7201 gttcccgctg aaaaataccg atgcgatcct gaacgttatc gcgcaaacgc ttcccgttaa
     7261 aattcagtct attacgcggt actggataaa catttcacca ctgtaaggaa aataattctt
     7321 atttcgattg tcctttttac ccttctcgtt cgactcatag ctgaacacaa caaaaatgat
     7381 gatggggaag gtatgacgcc gttacgcgtt tttcgtaaaa caacaccttt ggttaacgcc
     7441 attcgcctga gcctgctgcc gctggccggt ctctcgtttt ccgcttttgc tgcacaggtt
     7501 aatatcgcac cgggatcgct cgataaagcg ctcaatcagt atgccgcaca cagcggattt
     7561 accctctcgg ttgacgccag cctgacgcgc ggcaagcaga gcaacggcct gcacggcgat
     7621 tacgacgtcg agagcggcct gcaacaactg ctggacggca gcggactgca ggtaaaaccg
     7681 ctgggaaata acagctggac gctggagccc gcgcccgcac caaaagaaga tgccctgacc
     7741 gtggtcggcg actggctggg tgatgcgcgt gaaaacgacg tatttgaaca tgctggcgcg
     7801 cgtgacgtga tccgccgtga ggatttcgcc aaaaccggcg caaccaccat gcgtgaggta
     7861 cttaaccgca tccctggcgt cagcgcgccg gaaaacaacg gcaccggcag ccacgacctg
     7921 gcgatgaact ttggcatccg gggcctgaac ccacgcctcg ccagccgctc gaccgtcctg
     7981 atggacggca tccccgtccc cttcgcccct tacggtcagc cgcagctttc actggctccc
     8041 atttcgctcg gcaacatgga tgccattgac gtggtacgcg gtggtggtgc ggtgcgttac
     8101 ggaccgcaga gcgtgggcgg cgtggtgaac tttgttaccc gtgccattcc gcaggacttt
     8161 ggtatcgagg cgggcgtgga aggtcagctc agcccaacct cttcacaaaa caacccgaaa
     8221 gagacgcaca acctgatggt gggcggcaca gcggacaacg gttttggcac cgcgctgctc
     8281 tactccggca cgcgcggcag tgactggcgc gagcacagcg ccacccgcat cgacgacctg
     8341 atgctgaaaa gcaaatatgc gccggatgag gtgcacacct tcaacagcct gctgcaatat
     8401 tacgacggtg aagccgacat gcccggtggc ctgtctcgcg cggattacga cgccgatcgc
     8461 tggcaatcca cccgcccgta tgaccacttc tggggtcgtc gcaagctggc gagcctgggc
     8521 taccagttcc agccagacag ccagcataaa ttcaacattc aggggttcta cacccaaacc
     8581 ctgcgcagcg gctacctgga gcaaggcaaa cgcatcaccc tctcgccgcg taactactgg
     8641 gtgcgcggta ttgagccacg ctacagccag atctttatga tcggcccttc cgcgcacgaa
     8701 gtgggcgtgg gctatcgcta tgtgaatgaa tcaacgcatg aaatgcgtta ctacaccgcc
     8761 accagcagcg ggcagttgcc gtccggctca agcccttacg accgcgatac gcgttccggc
     8821 accgaggcgc acgcctggta tctggatgac aaaatcgaca tcggcaactg gaccatcacg
     8881 ccgggtatgc gtttcgaaca tatcgagtca taccagaaca acgccatcac aggcacgcac
     8941 aaagaagtga gctataacgc accgcttccg gcgttgaacg tgctctatca cctgactgac
     9001 agctggaatc tttatgcaaa cactgaaggc tcgttcggca ccgtacagta cagccagatt
     9061 ggcaaggctg tgcaaagcgg caatgtggaa ccggaaaaag cgcgaacctg ggaactcggt
     9121 acccgctacg acgacggcgc gctgacggcg gaaatggggc tgttcctgat taactttaac
     9181 aatcagtacg actccaacca gaccaacgac accgtcactg cacgtggcaa aacgcgccat
     9241 accgggctgg aaacgcaggc acgttacgat ctgggtacgc taacgccaac gcttgataac
     9301 gtttccatct acgccagcta tgcgtatgtg aacgcggaaa tccgcgagaa aggcgacacc
     9361 tacggcaatc tggtaccatt ctccccgaaa cataaaggca cgctgggcgt ggactacaag
     9421 ccaggaaact ggacgttcaa tctgaacagc gatttccagt ccagccagtt tgcggataac
     9481 gccaatacgg tgaaagagag cgccgacggc agtaccggcc gcattcccgg cttcatgctc
     9541 tggggcgcac gcgtggcgta tgactttggc ccgcagatgg cagatctgaa cctggcattc
     9601 ggtgtgaaaa acatcttcga ccaggactac ttcatccgct cttatgacga caacaacaaa
     9661 ggcatctatg caggccagcc gcgcacgctg tatatgcagg ggtcgttgaa gttctgatgt
     9721 gttaacgccc ggcttgccgg gcttttagct ggaatgtgat tatgttggca tttatccgtt
     9781 ttctttttgc aggcctgctg ctggtgatca gccacgcctt tgccgccatg gttcaggacg
     9841 aacacggcac gtttacactc gaaaaaacgc cacaacggat tgtggtgctg gaactctcgt
     9901 tcgccgatgc gctggccgcc gtggacgtca gcccgatcgg tattgccgac gataacgatg
     9961 caaaacgcat cctgcccgaa gtgcgtgcgc acctgaaacc gtggcagtca gtcggaacgc
    10021 gcgcgcagcc gagcctggaa gccattgccg ctctgaaacc agacctgatc attgccgaca
    10081 gcagtcgcca tgcgggggtt tacatcgcct tgcagcaaat cgcgccggta ctgctgctta
    10141 agtcccgcaa cgaaacctac gctgaaaatt tgcaatctgc ggctatcatc ggcgaaatgg
    10201 tgggtaaaaa gcgagagatg caggcacgtc tggaacaaca taaagagagg atggcgcagt
    10261 gggccagcca gcttcccaaa gggacacgcg tggcctttgg cacatcacgc gaacagcaat
    10321 tcaacctgca tactcaggag acctggaccg gcagcgtgct ggcctctctg gggctgaacg
    10381 ttcccgctgc gatggcgggt tcgtccatgc cgtccatcgg cctggagcaa ctgctggcgg
    10441 tcaatcctgc ctggctgctg gttgcccact atcgcgaaga gagcattgtt aaacgctggc
    10501 aacaagatcc gctctggcag atgttaaccg ccgcgcagaa gcagcaggtt gcttcggtcg
    10561 acagtaacac ctgggcgcgg atgcgcggta tttttgctgc agagcgtatt gccgctgaca
    10621 cggtaaaaat cttccaccat cagccgctta ccgttgtgaa atgaccgcga taaaacaccc
    10681 gatgctgctg tgggggcttc ccgttgcagc acttattatt attttctggc tgagtctgtt
    10741 ttgctactcg gccattcctg tttccggagc agatgcaacc cgcgccctgc tgcctggaca
    10801 cacgccaacg ctaccagaag cgctggtgca aaaccttcgt ttgccacgaa gcctggtcgc
    10861 cgttctgatc ggcgcaagcc tggcgctcgc gggcacgctg ctgcaaaccc tgacccacaa
    10921 cccaatggcc tctccttcac tgctcggcat taacagcggc gcggcgctgg ctatggcgct
    10981 taccagcgcg ctgagtccga cgccgattgc aggctattct ctgtcgttca tcgcggcatg
    11041 cgggggcggc gtgagctggc tgctggtcat gaccgcagga ggcggatttc gtcataccca
    11101 tgacagaaac aaactgatcc tcgcgggtat cgcgctgtcg gccttttgta tgggccttac
    11161 ccgcatcacc ctgctgctgg ccgaagatca tgcttacggc atcttttact ggctggcagg
    11221 cggagtgtcc cacgcccgct ggcaggatgt ctggcagctc ttgccggtgg tggtcactgc
    11281 agtccctgtc gtgttactgc tggcgaatca actgaacctg ctcaacctca gcgacagcac
    11341 cgcccatacg ctgggagtga acctgacgag gctacgtttg gtcatcaata tgttagtgct
    11401 gcttctggtt ggtgcgtgcg tcagcgtggc aggtccggtg gcgtttatcg gtctgctggt
    11461 gccacatctg gcgcgcttct gggcaggctt cgatcagcgc aacgtactgc cagtgagcat
    11521 gctgctgggg gccacgctga tgttgctggc agatgtactc gcacgcgcgc tggccttccc
    11581 cggagatctg cccgcaggcg cagtgctggc gctgattggc agcccttgct ttgtctggct
    11641 tgtgaggagg cgaggatgaa aattgcgctg gttattttca tcacccttgc cctggcgggc
    11701 tgtgcgctgt tatcactcca tatgggagtg atccccgtgc cgtggcgcgc gctgctgacc
    11761 gactggcagg ccggacgcga gcattattat gtattgatgg agtaccgact gccgcgcttg
    11821 ctgctggcac tgtttgtcgg tgcagccctc gccgtggcgg gcgtgctgat acaggggatt
    11881 gtgcgcaacc ctctggcatc accggatatt ctcggcgtta accatgccgc cagcctggcc
    11941 tctgtggggg ctctacttct tatgccgtca ctgcccgtga tggtgctgcc gctgctggcc
    12001 tttgcgggcg gcatggcggg gttgatatta ctgaagatgc tggcaaagac ccaccagccg
    12061 atgaagctgg cgctcaccgg cgtggcgctt tctgcatgct gggccagcct gacggattat
    12121 ctgatgctct cgcgcccgca ggatgtgaac aacgccctgc tgtggctgac cggcagctta
    12181 tggggccgtg actggagctt tgtgaagatt gccatcccgc tgatgatttt atttctgccg
    12241 ctgagcctga gtttttgccg cgatctcgac ctccttgcac tcggcgatgc gcgcgccacc
    12301 acgctcggtg tgtcggtgcc ccatacccga ttctgggctt tgttactagc tgtcgccatg
    12361 acatctaccg gcgtggccgc ctgcggcccg attagcttta ttggtctcgt ggtgccgcat
    12421 atgatgcgta gcatcaccgg tggacgtcac cgcagactgc tgcctgtttc agccctgaca
    12481 ggtgcgttgc tgttggtggt tgccgatctg ctggcgagaa ttattcatcc cccactggag
    12541 ctcccggttg gcgtgctgac cgccattatc ggtgcgccgt ggtttgtctg gttgcttgtg
    12601 agaatgcgat aaatgacttt acgaactgaa aatctgacgg tcagttacgg gacagacaag
    12661 gtacttaacg acgtttcact ctcactgcca acggggaaga tcaccgccct gatcggccct
    12721 aacggttgcg ggaaatcgac gctgttaaac tgtttttcgc ggcttttaat gccgcagtct
    12781 ggcaccgtat ttctcggcga taatcccata aatatgctct catcacgcca gttggcccgc
    12841 aggctttcgc tgctgcctca gcaccattta acgccagagg ggatcacagt ccaggagctg
    12901 gtttcgtatg gtcgtaatcc ctggctgtca ctctgggggc gtctctccgc tgaagacaat
    12961 gcacgagtta atgtcgccat gaaccagacc cggatcaatc atcttgccgt tcgtcggtta
    13021 accgagcttt ccggcggtca gcgccagcgc gcatttctgg cgatggtcct ggcccagaat
    13081 acgcccgttg tattacttga tgagccaacc acctatcttg atatcaatca ccaggtggac
    13141 ctgatgcggt tgatgggcga actccggact caggggaaaa cggtggtcgc tgtgctgcac
    13201 gaccttaatc aggctagccg gtactgcgat caactggtgg taatggcaaa cggacatgtt
    13261 atggcgcaag gcacaccaga agaggtgatg accccaggat tgctgagaac agtattcagc
    13321 gtggaagcgg aaatacaccc cgagccggta tctggcaggc cgatgtgcct aatgaggtag
    13381 attgcacagg ccgtaagaac caaaccacga ctgaatgaaa ctggactggc gccagcaagc
    13441 ctgttcagac tggggctgaa cttttccgga ctctgaaaga ttaccaatac tcatcgtcca
    13501 tccgcttgct ttaggctgac aggttcataa tcaacgcaaa ccagagctgt acaggcttgg
    13561 gcgcggcttt caaaccagtc gtgatcacgg caatcaattt tgaactctgc ttaacggaca
    13621 tttctgtata acccttacgg caacgaaaaa cgcgaagtta aaattttaga aacccaaaaa
    13681 cgtgacatga ctaagtttag atttcagggg ggagatcaaa aaatttcgct ctgtgccaga
    13741 gcggacattc acggagctgg ttcattacca atgaggttgg gcttttgagg ataaatcaat
    13801 gatcagacgc caacgtaaat caaaagcaac cctggaacgg aattgctaat ccagtttctg
    13861 accatcgatt tttctaaaaa gtgtgcgttt gctactactt aggtaggtgc agctttctta
    13921 atcaccggca gccacgttat acaggccagt tgatggatcg attgttatca atgatatctt
    13981 catgagtcgg tgtctcaccc agcttaccga agctggcata aagtgaaggc agacgggccc
    14041 gtccttctcc ctttttcgcc agagggaaag cgcgaagcat ggtggcagcc tcccagtcac
    14101 aacaatagga tggtgtgcac ggctgctgac gccatgattc agcgatagag ccggaaaata
    14161 cggggtcaaa gccggtatca ttaaccagag tcatcgtgac ctgtactgcg gctggatgat
    14221 ctcctgctac tgcaactgct aggcgaccgc ggctcccttc aggtagtctg ttgtggtcaa
    14281 ctaaaactgg cctccgcgtt agagtttttc cagtatcggt tttctgattc gtttggtggt
    14341 aacccaccat tatattcgtg cggtcttagt gcgctgtaat atccaacgat atagtccgtt
    14401 attgcgtgag ctgcatcgct gaagcttaca tagcccgtcg ctggcaccca ttagttcttc
    14461 agactcctga agaagcgctc cattgggctg ttatcccagc agtttccacg ccggctcata
    14521 ctctgtctga tctggtatcg ccacagtaac tgccggaact gcctgctcgt ataatgactg
    14581 ccttgatcgc ttggaacatc accccgacgg gcttaccacg ggtttcccat gccatttcca
    14641 gtgctttcat ggtaagcctg ctgtccggcg agaacgagat ggcccagccc actggtttct
    14701 tgcgaacagg tcgagaacaa cggcgaggta cgcccagcgc ttacccgtcc agagtagagt
    14761 aagaggcagg gcgtagtcgg actatttccc tgcctctcct ccccgaaccg gacgtgcacc
    14821 tttcagcgca tccggctctc catttaaatg ctggcgaacg ccattgccac ttctgtaaag
    14881 cgcgatgtat acgtgtttct ggtctccgtc ctcagatagg gattaccttc gggtagccgc
    14941 cagcggaaca gcttcttgcc ttgccccacc aaccggtaca gtatttcgcc gctgagcttg
    15001 ccgtgattgg ttttaccaaa taaaacccac gttttgctct gacccggttt cggtgattta
    15061 caccaccacc tcatcaggga agcgatacct gtacggtatt tgcgggccag ccagtgagcc
    15121 agcttccaga acacgacacg gtcgatataa ctgaagactt ggccttaaaa tcaacgaact
    15181 gatagaacat ggcccagcct ttcagttttc ggttgagttg ttcagccata tcgactttgc
    15241 tttcactgta gttgcctgat aacagtgctg tcagcgatgc ggcgaagttt ctggctttct
    15301 cctgcgggat cgttgagacc actcgcatct cgccataacg actgcgtttg cgaatgatcc
    15361 tgtgccccag aaagataaag ccgtcattaa catgggtgat tttagtctta tccatgttca
    15421 gcctgagttt cagactgcct tcgagcacac cccgacactc ctccctgatg gcttccgcct
    15481 gtgctttggt gcctttgacg atgaggacaa aatcatcggc atagcggcag tacgccaccg
    15541 cgggtttcca ctgccagttt tctctgaccg ccgtacttcg gccccgttgg atactgttat
    15601 tccagtacca ccgatctttt ctggctttcc cgctcaggta gcgctcatgc aggtattgat
    15661 cgaactcatt cagcatgatg ttcgataata gcggcgatat aacaccgccc tgtggcacac
    15721 cttcactggc cgcccgaaag agaccgacat cgatatgtcc cgcttgatgg ttttccacag
    15781 cagagtcatg aaacgtgcgt cactgatcct gcggcgtaca gccttcatca gcagtcgatg
    15841 atgtacggtg tcgaagtaac tggacaggtc gccttcaatc acccagcgtc cccgggtttc
    15901 accacagtct gtgagctgta atttcaccgt gcggatcgcg tggtggacac tgcgctcagg
    15961 ccggaagcca tatgagagcg tatgaaaatc actctcccat atcggctcca tcgccatcag
    16021 catggcccgc tgaacaatac gatcccgcaa cgcggggata cccagtggtc gcagtttgcc
    16081 gttgctttta gggatgtaaa cccgtctggc gggcaagggc tggtagtggc ctgagagtaa
    16141 ttcatccctg aggatttgca gctcaacagc cagtctggcc tgtagcattg ttttgttcac
    16201 gccatcaacg ccgggggtat gggccccctt tgatgaaagc gtgatccgcg ccgcttcagc
    16261 cagccattct ggttgtgtta tcagacgcag cagccgttga atccgtaggg acggatcggt
    16321 gactgcccat gtggcaagct tgcgttgcat ttcgctgatt atcaaaggtc ttcacctcgt
    16381 taggtcagtt aattcacgtc gcaaacacat tcaaactgct tcccttcgcc atgtaatggg
    16441 ctttccccat cgcggactac tacggaagct ccgccagcca gcgcgtcatc ggagccatgc
    16501 ccccttaaca tccgtcgctg accttccccg gttacctgcc tggactcagg catactgagg
    16561 aggctgcccg tcgcactctt atccttgctt gccgcaagtt ggcagaagtc agcaacgcaa
    16621 gcgtgataga cgctgctgcc ccggtgtttc gcatacatgt caaacacctt cgaccggcag
    16681 tgcttacgta tcactgccag ttcctcctgc acggcctgtc agatcacgta ggccgtggtg
    16741 acgttttcaa cccacagagg cggattaacg ggttcatgtt cttcagcctt tcagtactta
    16801 accttgagga tcatctcggc ttagtgatct cgcctcaatc cccgttgtca gcgggttaca
    16861 tcaccctgcg gcatgccgca ggtcactgcc gctcaggttc tccaccgtca cacccggtgg
    16921 gattgttggg tttctcatcg tgagttaccg gctcaatatt ccagacagac tcgcggttca
    16981 tttaagcatc catgcccgcc ctgaactccg ggcacactat aggtcacatc accgcaccac
    17041 acctgatttg gttccgttac ggcgaactgt cgctcaagat gattcgggat agcaacgtgc
    17101 tcatgaccgc cacgcttata ccggtgagtc ggctgctggc aactgaccag ccccagctct
    17161 tcatgagtct gccagcaagc cagcgcccca tctggtagcc tctctgggtt gccattgtgg
    17221 cgatgcttct tgctccggca gagccgtggc tgatgccatg cagttcaagt acctggctgc
    17281 gtaatacagc cgtctgccgt ctggtttttc aggacggttt ttccagtatt tgtagctgct
    17341 gcgatggacc ccgaacacat ggcagagagt ggccacagga taacgcgccc tgagtttccc
    17401 gattatcgaa aactgttcag ggagtctgac atcaagagcg cggtagcctt tttaatattt
    17461 cattttccat ttcaatacgt tgtagctttt cctgagctca cggatttcaa tttgttccgg
    17521 ggtaatgggg gaggcttttg gtgtttttcc ctgccgctca tcacgtaatt gtttcaccca
    17581 tcgcgtcatt gtggaaaggc cgacatccat agcgctggct gcatctgcca cggtgtattt
    17641 ctggtcaacg accagttgag cggattcgcg tttaaactct gcgctgaaat ttcttttttc
    17701 attatggcac ctgtgttgtt ctgaggtgag catatcactc tgttcaggta gctaaattta
    17761 gtgtgccacc tcaaggttct tagtgagccg tttttaaaag atatgataat atattattgt
    17821 ttataattgt tgatgtttga tttagtagta tataaagttc accaccttta ttaggctttc
    17881 ctttatctct acttactggg tgccagaaac tttaaatttt aaacggaggg ggcattttgt
    17941 ttaaagcaaa tcatgttccg gtattaatgt atcatcatgt cagccattgc ccaggactgg
    18001 ttacactttc tcccgagaca ttccggaaac aaatgaatgg ttggctgaaa acaactggaa
    18061 aacactgtca tcagatgaac tggagttttt ttatcggggc ggaaaacttc cccgtaaagc
    18121 gttatgttga catttgatga tggatacctt gacaactggt ttcaggtata tcctttatta
    18181 aacgagttta atctcaaggc acatattttt ttaattacca gttttattgg aaatggtccg
    18241 gttcgtcact ctcctggaaa ggaatattct catcgcgatt gcgaacatca aatagcaacc
    18301 gggaatgctg ataatgttat gcttcgctgt ctgagtgaac gaaatgttgc aatctggtct
    18361 ggtcgaattt catgttcata cacatactca tacacgttgg gataaaaagt tcacttcacg
    18421 agaagaacag tgtaaacatc ttcggcagga cttattgagc ggagagaata tttaaaaaaa
    18481 atgacaggaa aatgcagtaa acatttgtgt tggccggaag gttattataa caaggattat
    18541 attcagatcg ctgaagaact tggattccat tatttatata caacagaaag aagatgaatg
    18601 ctcctgctaa aggaactaca cggataggaa gaataagcac caaggaacgg gaaaattgcg
    18661 tatggctgaa aagacgactt ttttattata caacaccgtt tttttcatcg ttgctggccc
    18721 ttcataaggg gccaagatta ccggatgact aataatgaat atactattta cggaatcatc
    18781 accgaatata ggtggtcagg aattacaggc tgttgctcaa atgaaggccc tgaagaaaat
    18841 ggggcattca gttctgcttg tctgcaggga gaacagcaaa attgcttttg aagccagtaa
    18901 gtttggaatt gatatcacat tcgcgttatt tcgaaacagt cttcacattc ctactgtatg
    18961 gagattactc ggaatagttc atagttttca gcccgatgca atcgttgtca cagtggacat
    19021 gatagtaata tgttggtttg gtacggtttt ttacctggaa acatccattc agaattatca
    19081 ggcaaaagac atatttgaca cgaaaaacaa aatttttttc aataaatcat ttttgcgatg
    19141 aggtgattgt tcccggaaca aatatgaaga cacatctgga gcaggaagga tgtcgaactc
    19201 gggttactgt tgtgcctcct ggctttgatt tccaggaatt atacgttgat tcccgaaaca
    19261 gtttgcctcc gagtgttctt tcctggctgg cgtcccgaag aggatgcccc gtaatgctca
    19321 ggtaggaatg ttgcgcccgg aaaaagggca cgaatttatg ttgaatttac tgttccattt
    19381 aaaaatgaat ggacgacagt tctgttggtt gattgtgggg tctggttcac ctgaactgcg
    19441 gaacatttac agtatcagat tgacagtatg ggcatgcatg atgatgtttt tattgctgac
    19501 aatgtttttc ctgccgcccc cgtatatcgg gttgccagtc tggtggttct gccttcagaa
    19561 acgaatcttt tggtatggtg ctggcagaag catcggcatt ttctgtgcct gtagtggcca
    19621 ctcagattgg tggaatccct gaggttattc agaacaacca gaccgggaca ttgttaccag
    19681 caagtaataa gcacgcatgg atgtgcgccc tgaatgattt tttaatgacc ctgggcgttt
    19741 ttatcagatg gctcgcctgg caaaacagga tatagaagag cggtttgata ttaataaaac
    19801 tgcgttaaaa tactcacatt agcgaagcaa agtacaatat gtttctataa gtaacttatc
    19861 atttatcggt ttccttaaaa ggattatttt ttcctcagat tcctaccggg gagtggaaca
    19921 cagaaatttc ggttcatgta cattttgcga tgttctataa atccggttgt cagtattcga
    19981 tattatatga actgcgttcc ttgccgtgca ttgaggattc tggcatacac cccacgttgc
    20041 cagcagaatt catcgccctt atttgcataa ggggggcgcg cctggaccgt ggacaatata
    20101 ttcttgagca ttatcgcttt gtgcaaaatt tgccagaaaa atattctaat ttttgtttcc
    20161 acaaaatcgg tatcattagt ccattcatcg ggaagatgga gagaattttg atatccagtg
    20221 ttctcccagt ggttttgacc gggaaggaga gttgatgttg tcattgttta caataaaaca
    20281 gttattgccc ggttaacatt ttcagtcatt ctgactcaaa tggacacatt gcttttattg
    20341 gcggattaca gggagcccta aaaataccgg actgatgtta ttcggtgcgc aacccgggct
    20401 gttatgggat tttcccaaac ggattatttt gaagcttttg tgcgttgatg aaagcttgca
    20461 atatctctga gtgtctggca gtcagtgagc acagtcatgt tttccggcaa ttgagatact
    20521 ggtatcagaa acgcaaaacc tttgttgcgg tctatagtga tttctgggag tctgtagcag
    20581 gaaaaacctg tggtgactgg tacagattac caacccaggt gattcgaaag ccgctaagcg
    20641 atatagccag taaaaaacgc tctgagtacc gaaaacgata cgctttgctg gattatatcc
    20701 atgaaactac tatcagctct ttggatgcat atcctgtaca ctcagaacat cagaatttaa
    20761 attaaggttt gatgtattct ctgaataaaa cagtaatgat aattttggta gaggcattcg
    20821 cactaaataa tgaaaaaata taaatctgag tttattcctg aatttaagaa aaattacctt
    20881 tcccctgttt actggtctac atggttcctt ttgggaatga ttgcaggtat ttcaatgttt
    20941 cccccttcat tcagagatcc tgtcttggca aaaatagggc gttgggcggg cagattgagc
    21001 aaaaaagctc gtcgcagggc gacgattaat ttatcgcttt gtttcccaga aaagagtgat
    21061 acagaacggg aaataattgt cgacaaaatg tttatcacag cattgcaatc catagtgatg
    21121 atggcagaac tggcaattcg tggtccggaa aagttccaga aacgagtgtt ctggaaaggc
    21181 ctcgaaattc ttgaggaaat tcgacacaat aatagaaatg tgatttttct ggttccccat
    21241 ggctggagcg tggatattcc tgcaatgttg ctggcagctc agggaaaaaa aatggccgcc
    21301 atgtttcatc agcaacgaaa tccagtgatt gattatgtct ggaattcagt acggcgtaaa
    21361 ttcggggggc gcttacatgc ccgggaggat gggataaaac catttattca gtcagtacgc
    21421 cagggatact ggggatatta cctcccagat caggatcatg gtcctgaata cagtgaattt
    21481 gctgattttt ttgcgaccta taaagcgaca ttaccaatca ttggacgtct gatgaacatc
    21541 agtcaggcta tgattatacc acttttcccg gtttatgatg aaaaaaaaca tctactgact
    21601 attgaaattc ggccaccaat ggatgcttgc attgccagcg cggacaataa aacgattgcc
    21661 cgacaaatga acaaaacagt ggaaattttg gtggggccac atccggaaca gtatgtctgg
    21721 gttttaaaat tgttaaaaac acgcaaatca aacgaagcgg acccgtaccc ttgaaattat
    21781 aaagtacaag tatttccact agttgtttgt aagcgtacag cctgaaccgt ctggtcagaa
    21841 tctgacgaat tagacaaagt ggtgtccacc aaataagtag tgggaaccaa tgaggtagcc
    21901 tgagtttaac ggacactcct tcctgaaata gaatggcatc agaaggagct aataatgagc
    21961 agaaaaaccc aacgttactc taaagagttc aaagccgaag ctgtcagaac ggttcttgaa
    22021 aatcaacttt cgatcagtga aggcgcttcc cgattatctc ttcctgaagg cactttagga
    22081 caatgggtta ccgccgccag aaaagggctc ggtactcctg gttcccgcac ggtggctgaa
    22141 ctggaatctg aaattctgca actgcgtaag gcgttaaatg aagctcgcct tgagcgagat
    22201 atattaaatt gcacaggagt cgctgaaaaa tacgcgttaa tcgaacaatg gcgacaacaa
    22261 tttcccattg aagcgatgtg tcaggtattt ggtgtatcca ggagcggtta ttacaactgg
    22321 gtacagcatg aaccctcaga cagaaaacaa agtgatgagc ggctaaaact ggagattaag
    22381 gtggcacata tccgcactcg cgaaacatat ggaacccggc ggctccagac ggagctggca
    22441 gagaatggca tcatcgttgg tcgtgaccga ctggcacgtc ttcgtaagga gctaaggcta
    22501 cgctgtaagc agaaacgcaa gttcagagcg actacgaact cgaaccacaa tctgccagtt
    22561 gcgccaaatc tgctgaacca gacgttcgct cctacagcac caaatcaggt ctgggtggcg
    22621 gacctgacgt atgttgccac acaggaggga tggttgtacc tcgctggcat caaagatgtt
    22681 tatacgtgcg aaattgtcgg ctacgccatg ggagagcgca tgacaaaaga gctgacaggt
    22741 aaagccctgt ttatggcgct caggagccag cgcccacctg ccgggctaat ccaccactct
    22801 gatcgaggtt cacagtactg cgcatacgat taccgggtca tacaggagca gtttggtctg
    22861 aaaacatcaa tgtcgcgtaa aggtaactgt tacgacaacg ctccgatgga aagcttctgg
    22921 ggaacgctga aaaatgagag cctgagccac tatcgtttta ataaccggga tgaagccatc
    22981 tcagtaatac gggaatacat tgagattttc tacaatcgtc agcgtcgtca ctctcgtctg
    23041 gggaatatct ccccggcagc cttcagggaa aaatatcatc agatggctgc ttaaaaaaag
    23101 aacaaatggt agtgtccgct attgccagta cacctcaaca ttccaccatg cattacgatt
    23161 aacgccgcat agccagttga actttgctac tttgtgagag gtagtacctt ctatccagtg
    23221 cgaatttaat taatggaata aatgattatg agtgaaaatg atacaatccc aaagaagtct
    23281 acaagtcaga ttaacaaagc ggtattcttt acatctgctt tgctaatttt cc
//