Mercurial > repos > aaronquinlan > multi_intersect
diff BEDTools-Version-2.14.3/src/pairToPair/pairToPairMain.cpp @ 0:dfcd8b6c1bda
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author | aaronquinlan |
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date | Thu, 03 Nov 2011 10:25:04 -0400 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/BEDTools-Version-2.14.3/src/pairToPair/pairToPairMain.cpp Thu Nov 03 10:25:04 2011 -0400 @@ -0,0 +1,188 @@ +/***************************************************************************** + pairToPairMain.cpp + + (c) 2009 - Aaron Quinlan + Hall Laboratory + Department of Biochemistry and Molecular Genetics + University of Virginia + aaronquinlan@gmail.com + + Licenced under the GNU General Public License 2.0 license. +******************************************************************************/ +#include "pairToPair.h" +#include "version.h" + +using namespace std; + +// define our program name +#define PROGRAM_NAME "pairToPair" + +// define our parameter checking macro +#define PARAMETER_CHECK(param, paramLen, actualLen) (strncmp(argv[i], param, min(actualLen, paramLen))== 0) && (actualLen == paramLen) + +// function declarations +void ShowHelp(void); + +int main(int argc, char* argv[]) { + + // our configuration variables + bool showHelp = false; + + // input files + string bedAFile; + string bedBFile; + + // input arguments + float overlapFraction = 1E-9; + int slop = 0; + string searchType = "both"; + + // flags to track parameters + bool haveBedA = false; + bool haveBedB = false; + bool haveSearchType = false; + bool haveFraction = false; + bool ignoreStrand = false; + bool requireDifferentNames = false; + bool haveSlop = false; + bool strandedSlop = false; + // check to see if we should print out some help + if(argc <= 1) showHelp = true; + + for(int i = 1; i < argc; i++) { + int parameterLength = (int)strlen(argv[i]); + + if((PARAMETER_CHECK("-h", 2, parameterLength)) || + (PARAMETER_CHECK("--help", 5, parameterLength))) { + showHelp = true; + } + } + + if(showHelp) ShowHelp(); + + // do some parsing (all of these parameters require 2 strings) + for(int i = 1; i < argc; i++) { + + int parameterLength = (int)strlen(argv[i]); + + if(PARAMETER_CHECK("-a", 2, parameterLength)) { + if ((i+1) < argc) { + haveBedA = true; + bedAFile = argv[i + 1]; + i++; + } + } + else if(PARAMETER_CHECK("-b", 2, parameterLength)) { + if ((i+1) < argc) { + haveBedB = true; + bedBFile = argv[i + 1]; + i++; + } + } + else if(PARAMETER_CHECK("-type", 5, parameterLength)) { + if ((i+1) < argc) { + haveSearchType = true; + searchType = argv[i + 1]; + i++; + } + } + else if(PARAMETER_CHECK("-f", 2, parameterLength)) { + if ((i+1) < argc) { + haveFraction = true; + overlapFraction = atof(argv[i + 1]); + i++; + } + } + else if(PARAMETER_CHECK("-slop", 5, parameterLength)) { + if ((i+1) < argc) { + haveSlop = true; + slop = atoi(argv[i + 1]); + i++; + } + } + else if(PARAMETER_CHECK("-ss", 3, parameterLength)) { + strandedSlop = true; + } + else if(PARAMETER_CHECK("-rdn", 4, parameterLength)) { + requireDifferentNames = true; + } + else if(PARAMETER_CHECK("-is", 3, parameterLength)) { + ignoreStrand = true; + } + else { + cerr << endl << "*****ERROR: Unrecognized parameter: " << argv[i] << " *****" << endl << endl; + showHelp = true; + } + } + + + // make sure we have both input files + if (!haveBedA || !haveBedB) { + cerr << endl << "*****" << endl << "*****ERROR: Need -a and -b files. " << endl << "*****" << endl; + showHelp = true; + } + + if (haveSearchType && (searchType != "neither") && (searchType != "both") && (searchType != "either") && (searchType != "notboth")) { + cerr << endl << "*****" << endl << "*****ERROR: Request \"both\",\"neither\",\"either\",or \"notboth\"" << endl << "*****" << endl; + showHelp = true; + } + + if (strandedSlop == true && haveSlop == false) { + cerr << endl << "*****" << endl << "*****ERROR: Need a -slop value if requesting -ss." << endl << "*****" << endl; + showHelp = true; + } + + if (!showHelp) { + + PairToPair *bi = new PairToPair(bedAFile, bedBFile, overlapFraction, searchType, + ignoreStrand, requireDifferentNames, slop, strandedSlop); + delete bi; + return 0; + } + else { + ShowHelp(); + } +} + + +void ShowHelp(void) { + cerr << endl << "Program: " << PROGRAM_NAME << " (v" << VERSION << ")" << endl; + + cerr << "Author: Aaron Quinlan (aaronquinlan@gmail.com)" << endl; + + cerr << "Summary: Report overlaps between two paired-end BED files (BEDPE)." << endl << endl; + + cerr << "Usage: " << PROGRAM_NAME << " [OPTIONS] -a <BEDPE> -b <BEDPE>" << endl << endl; + + cerr << "Options: " << endl; + cerr << "\t-f\t" << "Minimum overlap required as fraction of A (e.g. 0.05)." << endl; + cerr << "\t\tDefault is 1E-9 (effectively 1bp)." << endl << endl; + + cerr << "\t-type \t" << "Approach to reporting overlaps between A and B." << endl << endl; + cerr << "\t\tneither\tReport overlaps if neither end of A overlaps B." << endl; + cerr << "\t\teither\tReport overlaps if either ends of A overlap B." << endl; + cerr << "\t\tboth\tReport overlaps if both ends of A overlap B." << endl; + cerr << "\t\tnotboth\tReport overlaps if one or neither of ends of A overlap B." << endl; + + cerr << "\t\t- Default = both." << endl << endl; + + cerr << "\t-slop \t" << "The amount of slop (in b.p.). to be added to each footprint." << endl; + cerr << "\t\t*Note*: Slop is subtracted from start1 and start2 and added to end1 and end2." << endl << endl; + + cerr << "\t-ss\t" << "Add slop based to each BEDPE footprint based on strand." << endl; + cerr << "\t\t- If strand is \"+\", slop is only added to the end coordinates." << endl; + cerr << "\t\t- If strand is \"-\", slop is only added to the start coordinates." << endl; + cerr << "\t\t- By default, slop is added in both directions." << endl << endl; + + cerr << "\t-is\t" << "Ignore strands when searching for overlaps." << endl; + cerr << "\t\t- By default, strands are enforced." << endl << endl; + + cerr << "\t-rdn\t" << "Require the hits to have different names (i.e. avoid self-hits)." << endl; + cerr << "\t\t- By default, same names are allowed." << endl << endl; + + + cerr << "Refer to the BEDTools manual for BEDPE format." << endl << endl; + + // end the program here + exit(1); +}